Thermo Fisher Scientific RBM6 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RBM6 (AAH46643.1, 1 a.a. approximately 601 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RBM6,uniProtId:P78332-1,ncbiNodeId:9606,antigenRange:1-1123,antigenLength:1123,antigenImageFileName:H00010180-B01P_RBM6_P78332-1_House_mouse.svg,antigenImageFileNamePDP:H00010180-B01P_RBM6_P78332-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MIQDKEVTLE YVSSLDFWYC KRCKANIGGH RSSCSFCKNP REVTEAKQEL ITYPQPQKTS IPAPLEKQPN QPLRPADKEP EPRKREEGQE SRLGHQKREA ERYLPPSRRE GPTFRRDRER ESWSGETRQD GESKTIMLKR IYRSTPPEVI VEVLEPYVRL TTANVRIIKN RTGPMGHTYG FIDLDSHAEA LRVVKILQNL DPPFSIDGKM VAVNLATGKR RNDSGDHSDH MHYYQGKKYF RDRRGGGRNS DWSSDTNRQG QQSSSDCYIY DSATGYYYDP LAGTYYDPNT QQEVYVPQDP GLPEEEEIKE KKPTSQGKSS SKKEMSKRDG KEKKDRGVTR FQENASEGKA PAEDVFKKPL PPTVKKEESP PPPKVVNPLI GLLGEYGGDS DYEEEEEEEQ TPPPQPRTAQ PQKREEQTKK ENEEDKLTDW NKLACLLCRR QFPNKEVLIK HQQLSDLHKQ NLEIHRKIKQ SEQELAYLER REREGKFKGR GNDRREKLQS FDSPERKRIK YSRETDSDRK LVDKEDIDTS SKGGCVQQAT GWRKGTGLGY GHPGLASSEE AEGRMRGPSV GASGRTSKRQ SNETYRDAVR RVMFARYKEL D

Target Information

DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.