Thermo Fisher Scientific COLQ Polyclonal Antibody
COLQ 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관하며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COLQ (Accession Q9Y215), corresponding to amino acid residues M208–G258 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852490 |
Product Specific Information
Antibody detects endogenous levels of total COLQ.
Target Information
COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase) is a 455 amino acid protein localized at the skeletal muscle end plate. It anchors catalytic subunits of asymmetric AChE to the basal lamina at neuromuscular junctions. Mutations in COLQ cause congenital myasthenic syndromes, rare autosomal recessive diseases characterized by muscle weakness, ophthalmoplegia, and resistance to anticholinesterase drugs. Eight isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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