Thermo Fisher Scientific Tet Polyclonal Antibody
Fruit fly 유래 Tet 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB와 ELISA에 사용 가능. Protein G로 정제된 고순도 항체이며, PBS/glycerol buffer에 보관. DNA 탈메틸화 연구 및 신경 발달 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Drosophila melanogaster (Fruit fly) DMAD protein (2494–2767 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.475 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3092392 |
Target Information
Dioxygenase that specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA.
N(6)-methyladenosine (m6A) DNA is abundant in early embryonic stages but decreases in late stages, acting as a regulator of gene expression.
Promotes differentiation of early germ cells in the ovary and contributes to neuronal morphology, development, and brain function.
By interacting with histone modifier wds, it binds to specific genes, modulates intragenic m6A DNA levels, and maintains transcriptional activation.
Also catalyzes the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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