Thermo Fisher Scientific NKCC1 Polyclonal Antibody
Human NKCC1 단백질을 인식하는 Goat 유래 Polyclonal 항체로, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 0.5 mg/mL 농도의 액상 형태이며, TBS buffer(pH 7.3, 0.5% BSA)로 안정화. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-NALQHSIRLSGVEDH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933176 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
NKCC1 mediates sodium and chloride transport and reabsorption. NKCC1 is a membrane protein important for maintaining proper ionic balance and cell volume. It acts as an electrically silent transporter system and is phosphorylated in response to DNA damage.
Three transcript variants encoding two different isoforms have been identified for NKCC1. Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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