
Thermo Fisher Scientific MAPK6 Monoclonal Antibody (4C11)
MAPK6 단백질을 인식하는 Thermo Fisher monoclonal antibody (clone 4C11). Western blot 및 ELISA에 적합하며 인간, 마우스, 랫트 반응성. 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C11 |
| Immunogen | MAPK6 (AAH35492, 612–721 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence (partial):
EVRKDEQVEK ENTYTSYLDK FFSRKEDTEM LETEPVEDGK LGERGHEEGF LNNSGEFLFN KQLESIGIPQ FHSPVGSPLK SIQATLTPSA MKSSPQIPHQ TYSSILKHLN
Target Information
The protein encoded by this gene belongs to the Ser/Thr protein kinase family and is closely related to mitogen-activated protein kinases (MAP kinases), also known as extracellular signal-regulated kinases (ERKs). These kinases are activated through phosphorylation cascades and serve as integration points for multiple biochemical signals.
This kinase is localized in the nucleus and is activated in fibroblasts upon treatment with serum or phorbol esters.
Tissue specificity: Highest expression in skeletal muscle, followed by brain. Also expressed in heart, placenta, lung, liver, pancreas, kidney, and skin fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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