Thermo Fisher Scientific DCPS Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DCPS. Recombinant protein control fragment (Product #RP-97297). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DCPS,uniProtId:Q96C86-1,ncbiNodeId:9606,antigenRange:7-103,antigenLength:337,antigenImageFileName:PA5-58865_DCPS_Q96C86-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58865_DCPS_Q96C86-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640427

Product Specific Information

Immunogen sequence: QLGKRKRELD VEEAHAASTE EKEAGVGNGT CAPVRLPFSG FRLQKVLRES ARDKIIFLHG KVNEASGDGD GEDAVVILEK TPFQVEQVAQ LLTGSPE

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 82%.

Target Information

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3->5 exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.