Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI2G2), TrueMAB
BTLA 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. Human 시료에 반응하며, Lyophilized 형태로 제공. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G2 |
| Immunogen | Full length human recombinant protein of human BTLA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor that downregulates immune responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon T cell activation. It remains expressed on Th1 cells but not on Th2 cells. BTLA interacts with HVEM (herpesvirus entry mediator), a TNF receptor superfamily member, forming an important regulatory pathway for lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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