Thermo Fisher Scientific CAD Polyclonal Antibody
Thermo Fisher Scientific의 CAD Polyclonal Antibody는 인간 CAD 단백질(잔기 150-200 영역)을 인식하는 토끼 유래 폴리클로날 항체입니다. Western blot, IHC, IP 등 다양한 응용에 적합하며, 액상 형태로 제공되어 4°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate.
This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis:
- Carbamoylphosphate synthetase (CPS II)
- Aspartate transcarbamoylase
- Dihydroorotase
This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, indicating a direct link between MAPK activation and de novo pyrimidine nucleotide biosynthesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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