Thermo Fisher Scientific PDE4B Monoclonal Antibody (OTI1B11), TrueMAB
Human PDE4B 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Flow cytometry에 적합. Affinity chromatography로 정제된 액상 제품이며, PBS/BSA/glycerol buffer에 보관. 신호전달 및 정신질환 관련 연구용으로 사용.
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- TA503478
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B11 |
| Immunogen | Full length human recombinant protein of human PDE4B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides act as second messengers regulating various cellular responses to extracellular stimuli such as hormones, light, and neurotransmitters. PDEs control cellular cyclic nucleotide levels and play a key role in signal transduction. The PDE4B protein specifically hydrolyzes cAMP, and altered activity has been linked to schizophrenia and bipolar affective disorder. Multiple splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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