Thermo Fisher Scientific USP3 Polyclonal Antibody
Thermo Fisher Scientific USP3 Polyclonal Antibody는 인간 USP3 단백질을 인식하는 Rabbit IgG 항체로, Western blot, IHC, ICC/IF, ELISA 등에 적합합니다. Protein A로 정제된 액상 형태이며, 높은 특이성과 재현성을 제공합니다.
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Thermo Fisher Scientific USP3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human USP3 (amino acids 31–130) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity.
An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families:
- Ubiquitin C-terminal hydrolases
- Ubiquitin-specific processing proteases (USPs)
- OTU-domain ubiquitin-aldehyde-binding proteins
- Jab1/Pad1/MPN-domain-containing metallo-enzymes
Among these families, USPs are the most widespread deubiquitinating enzymes across evolution. They release ubiquitin from conjugated proteins and possess conserved catalytic domains containing Cys and His boxes, with variable N- and C-terminal extensions that contribute to substrate recognition, localization, and protein interactions.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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