Thermo Fisher Scientific DNTT Monoclonal Antibody (4H5)
인간 DNTT 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 ELISA에 적합합니다. Affinity chromatography로 정제되어 있으며 PBS(pH 7.4)에 보존됩니다. TdT 표지자로서 급성 림프모구성 백혈병 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H5 |
| Immunogen | DNTT (AAH12920, 1–110 a.a) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDPPRASHLS PRKKRPRQTG ALMASSPQDI KFQDLVVFIL EKKMGTTRRA FLMELARRKG FRVENELSDS VTHIVAENNS GSDVLEWLQA QKVQVSSQPE LLDVSWLIEC
Target Information
Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyzes the polymerization of deoxynucleotides at the 3' hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template.
TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemias. Determination of TdT expression is most valuable when differentiating histologically between lymphoblastic lymphoma and Burkitt's lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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