Thermo Fisher Scientific RSV Fusion Protein Monoclonal Antibody (10B6)

Applications

Flow Cytometry (Flow)

• Tested Dilution: Assay-dependent

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

Mouse anti-Respiratory Syncytial Virus Fusion Protein antibody, clone 9C5 recognizes the Respiratory Syncytial Virus (RSV) Fusion protein, also known as F-protein.

Target Information

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps.
Its genome consists of single-stranded, negative-sense RNA that encodes three envelope glycoproteins: a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein.

The 63 kDa RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, forming syncytia or multinucleated giant cells.
The F proteins on the virus surface cause membranes of nearby cells to merge, forming syncytia.
While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.