Thermo Fisher Scientific HMGA1 Polyclonal Antibody
HMGA1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 적용 가능. 인간, 마우스, 랫트 시료에 반응. Affinity chromatography로 정제된 액상 형태이며, PBS와 50% glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HMGA1 (Accession P17096), corresponding to amino acid residues K62–Q107. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900003 |
Product Specific Information
Antibody detects endogenous levels of total HMGA1.
Target Information
HMGA1 encodes a non-histone protein involved in various cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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