Thermo Fisher Scientific CD204 Polyclonal Antibody
Thermo Fisher Scientific의 CD204 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot과 ELISA에 적합합니다. Recombinant CD204 단백질을 항원으로 사용한 Rabbit IgG 폴리클로날 항체로, 고순도 Affinity Chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 192–451 of human MSR1 (NP_6197291) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805716 |
Product Specific Information
Immunogen sequence:
LNIENLNGKI QENTFKQQEE ISKLEERVYN VSAEIMAMKE EQVHLEQEIK GEVKVLNNIT NDLRLKDWEH SQTLRNITLI QGPPGPPGEK GDRGPTGESG PRGFPGPIGP PGLKGDRGAI GFPGSRGLPG YAGRPGNSGP KGQKGEKGSG NTLTPFTKVR LVGGSGPHEG RVEILHSGQW GTICDDRWEV RVGQVVCRSL GYPGVQAVHK AAHFGQGTGP IWLNEVFCFG RESSIEECKI RQWGTRACSH SEDAGVTCTL
- Positive Samples: Mouse liver, Rat liver
- Cellular Location: Membrane, Single-pass type II membrane protein
Target Information
CD204 gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These macrophage-specific trimeric integral membrane glycoproteins are implicated in macrophage-associated processes such as atherosclerosis, Alzheimer’s disease, and host defense.
- Isoforms 1 and 2: Functional receptors mediating endocytosis of modified LDLs.
- Isoform 3: Non-functional receptor trapped in the endoplasmic reticulum, exhibiting dominant negative effects on types 1 and 2.
- Diseases associated with MSR1 include Barrett Esophagus and Prostate Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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