Thermo Fisher Scientific TWIST2 Monoclonal Antibody (3B2)
TWIST2 단백질을 인식하는 Mouse IgM 단일클론 항체로, Western blot 및 ELISA에 적합. 인간 시료 반응성 확인됨. 액상 형태이며 보존제가 없음. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:1,000
- ELISA (ELISA): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B2 |
| Immunogen | TWIST2 (54–140 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GSPSAQSFEE LQSQRILANV RERQRTQSLN EAFAALRKII PTLPSDKLSK IQTLKLAARY IDFLYQVLQS DEMDNKMTSC SYVAHER
Target Information
Binds to the E-box consensus sequence 5′-CANNTG-3′ as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A, and MEF2C.
Also represses expression of proinflammatory cytokines such as TNFA and IL1B.
Involved in postnatal glycogen storage and energy metabolism.
Inhibits premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by modifying internal signal transduction in response to external growth factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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