Thermo Fisher Scientific TWIST2 Monoclonal Antibody (3B2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

3B2

Immunogen

TWIST2 (-, 54 a.a. approximately 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TWIST2,uniProtId:Q8WVJ9-1,ncbiNodeId:9606,antigenRange:54-140,antigenLength:160,antigenImageFileName:H00117581-M20A_TWIST2_Q8WVJ9-1_House_mouse.svg,antigenImageFileNamePDP:H00117581-M20A_TWIST2_Q8WVJ9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: GSPSAQSFEE LQSQRILANV RERQRTQSLN EAFAALRKII PTLPSDKLSK IQTLKLAARY IDFLYQVLQS DEMDNKMTSC SYVAHER

Target Information

Binds to the E-box consensus sequence 5-CANNTG-3 as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.