Thermo Scientific™

DMS (dimethyl suberimidate)

Thermo Scientific Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of자세히 알아보기

Thermo Scientific Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.

Features of dimethyl suberimidate:

• Reactive groups: imidoester (both ends)
• Reactive towards: amino groups (primary amines)
• Longest of three similar imidoester crosslinkers, which include DMA, DMP and DMS
• Water-soluble
• Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
• Amidine bond retains net charge character of protein primary amine to which it reacts
• Reversible at high pH values
• Tool for study of quarternary structure of proteins

Product References
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
DMA (dimethyl adipimidate)
DMP (dimethyl pimelimidate)
DTBP (Wang and Richard`s Reagent)

사양

화학물질 반응성Amine-Amine

CleavableNo

설명DMS

분자량273.2

페길레이티드No

스페이서 암 길이11.0 Å

세포 투과성Yes

배송 조건Ambient

제품라인Pierce™

라벨링 방법Chemical Labeling

교차결합제 유형Homobifunctional

반응성 부분Imidoester

스페이서Medium (10 to 30 Å)

형태Powder

수량1 g

용해도Water

형식Standard

수용성Yes

제품 유형Crosslinker

Unit SizeEach