Thermo Fisher Scientific I-Ab Monoclonal Antibody (28-16-8S), FITC
FITC로 결합된 I-Ab 단클론 항체로 마우스 시료의 흐름세포분석(FACS)에 적합. Mouse MHC class II I-Ab를 인식하며 높은 특이성과 안정성 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Thermo Fisher Scientific I-Ab Monoclonal Antibody (28-16-8S), FITC
Applications
- Flow Cytometry (FACS)
Tested Dilution: Assay-dependent
Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 28-16-8S |
| Immunogen | Mouse MHC class II I-Ab |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; -20°C long term. Avoid freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539145 |
Additional Formats
- Unconjugated
- Biotin
- PE
- Custom conjugation available upon request
Product Specific Information
MA5-17757 targets I-Ab in FACS applications and shows reactivity with Mouse samples.
The immunogen is mouse MHC class II I-Ab.
Target Information
I-Ab (H2-Ab1, histocompatibility 2, class II antigen A, beta 1) is an MHC class II heterodimer composed of non-covalently associated alpha (31–34 kDa) and beta (26–29 kDa) chains.
MHC class II molecules present exogenously derived antigens to CD4+ T lymphocytes, aiding immune recognition. The beta chain contains six exons encoding leader peptide, extracellular domains, transmembrane domain, and cytoplasmic tail.
These molecules are expressed in antigen-presenting cells such as B lymphocytes, dendritic cells, and macrophages.
HLA and MHC antibodies are essential tools in Immunopeptidomics, enabling identification and characterization of neoantigens via LC-MS/MS.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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