Thermo Fisher Scientific Caveolin 1 Polyclonal Antibody, Biotin
Caveolin-1 단백질을 인식하는 Biotin-conjugated Polyclonal 항체로, Western blot 및 ICC/IF에 사용 가능. Human 시료에 반응하며, 고순도 액상 형태로 제공. TBS buffer(pH 7.3, 0.5% BSA) 보존, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DELSEKQVYDAH |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932814 |
Product Specific Information
- This antibody is expected to recognize both reported isoforms (NP_001744.2; NP_001166366.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
Caveolin-1 (CAV1) is a scaffolding protein within caveolar membranes that interacts directly with G-protein alpha subunits and regulates their activity. It plays a role in T-cell receptor (TCR)-mediated activation, binding with DPP4 to induce T-cell proliferation and NF-κB activation.
Mutations in the CAV1 gene are associated with congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, and partial lipodystrophy/congenital cataracts with neurodegeneration syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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