Thermo Fisher Scientific PDE4B1 Polyclonal Antibody, FITC
PDE4B1 단백질을 인식하는 FITC 결합 폴리클로날 항체로, 인간·마우스·랫트 반응성. WB, ELISA, IP 등 다양한 실험에 사용 가능. 고순도 친화 크로마토그래피 정제 및 안정한 액상 형태로 제공. 연구용으로만 사용.
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Thermo Fisher Scientific PDE4B1 Polyclonal Antibody, FITC
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide selective only for PDE4B1 subtype variant |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides act as second messengers that mediate various cellular responses to extracellular signals such as hormones, light, and neurotransmitters. PDEs regulate intracellular cyclic nucleotide concentrations and play key roles in signal transduction. The PDE4B1 protein specifically hydrolyzes cAMP, and altered activity has been linked to schizophrenia and bipolar affective disorder. Multiple splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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