Thermo Fisher Scientific SMN1 Recombinant Rabbit Monoclonal Antibody (8B10)
SMN1 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. 인체 시료에 반응하며 IHC(P) 및 ELISA에 적합합니다. 높은 순도(affinity chromatography 정제)와 안정적인 액상 형태로 제공되며, 장기 보관 시 -20°C 이하에서 안정적입니다.
- 카탈로그번호
- MA549923
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8B10 |
| Immunogen | A synthesized peptide derived from human SMN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092809 |
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains several genes and repetitive elements, making it prone to rearrangements and deletions. The telomeric and centromeric copies of SMN1 are nearly identical and encode the same survival motor neuron protein.
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), essential components of the spliceosome.
Mutations in the SMN1 gene are known to cause spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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