Thermo Fisher Scientific Perilipin 1 Polyclonal Antibody
Perilipin 1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 4°C 또는 -20°C 보관이 권장됩니다.
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- PA555046
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- pk
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Thermo Fisher Scientific Perilipin 1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:2,000 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Perilipin. Recombinant protein control fragment (Product #RP-88973). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645393 |
Product Specific Information
Immunogen sequence:
VCNAYEKGVQ SASSLAAWSM EPVVRRLSTQ FTAANELACR GLDHLEEKIP ALQYPPEKIA SELKDTISTR LRSARNSISV PIASTSDKVL GAALAGCELA WGVARDTAEF AANTRAGRLA SGGADLALGS IEKVVE
Highest antigen sequence identity to orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
Adipose tissue acts as an energy reserve and produces various physiologically important proteins such as LPL, leptin, Acrp30, resistin, and perilipin.
Perilipin is an intracellular neutral lipid droplet protein localized on the surface of lipid droplets and hormonally regulated. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A and inhibits hormone-sensitive lipase (HSL), which mediates triacylglycerol hydrolysis.
Perilipin expression is restricted to adipocytes and steroidogenic cells. Two isoforms, Perilipin A and B, are known and are produced through differential splicing of a single-copy gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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