Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI4F8), TrueMAB
CD4 단백질을 인식하는 Mouse Monoclonal Antibody (OTI4F8)로, Western blot과 IHC(P) 검증 완료. 인간 시료에 반응하며, PBS/BSA/glycerol buffer에 보관. 면역학 연구 및 HIV 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F8 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human CD4 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes (T helper cells) and may also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is detected in thymus, lymph nodes, tonsils, spleen, and specific regions of the brain and gut.
CD4 functions to initiate or augment T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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