Thermo Fisher Scientific Human LIMK1, His Tag Recombinant Protein

Thermo Fisher Scientific Human LIMK1, His Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use material in original packaging until exhausted.
• For larger sizes, aliquot preparation may reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
• Never store kinase diluted.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
• Protein Form: Catalytic

Target Information

LIMK1 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. It plays a role in brain development and contains LIM domains—highly conserved cysteine-rich structures with two zinc fingers. The LIM motif mediates protein-protein interactions. LIMK1 and LIMK2 form a subfamily with two N-terminal LIM motifs and a C-terminal kinase domain. LIMK1 may participate in intracellular signaling and is implicated in the visuospatial cognitive deficits associated with Williams syndrome.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.