Thermo Fisher Scientific PA2G4 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): Tested dilution 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGD

Target Information

This gene encodes an RNA-binding protein involved in growth regulation.
It is present in pre-ribosomal ribonucleoprotein complexes and may participate in ribosome assembly and rRNA processing.
The protein interacts with the ErbB3 receptor’s cytoplasmic domain, contributing to growth regulatory signal transduction.
It also acts as a transcriptional co-repressor of androgen receptor-regulated and other cell cycle genes via histone deacetylase interactions.
This protein is implicated in growth inhibition and differentiation induction in human cancer cells.
Six pseudogenes are located on chromosomes 3, 6, 9, 18, 20, and X.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.