Thermo Fisher Scientific HDAC3 Monoclonal Antibody (6F11)
HDAC3 단백질을 인식하는 Rabbit Monoclonal Antibody(클론 6F11)로, Western blot, IHC, ICC/IF에 사용 가능. 고순도 액상 형태로 제공되며, 1 mg/mL 농도. 연구용으로 세포 성장 및 전사 조절 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6F11 |
| Immunogen | Recombinant human HDAC3 protein (C-terminal 100aa, range 329–428) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.
This gene is regarded as a potential tumor suppressor gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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