Thermo Fisher Scientific GnRH-Receptor/LH-RH Receptor Recombinant Rabbit Monoclonal Antibody (GNRHR/2982R)
GnRH 수용체에 특이적인 재조합 토끼 단클론 항체로, 인간 시료에 반응합니다. ELISA 등 다양한 어플리케이션에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 4°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | GNRHR/2982R |
| Immunogen | Recombinant full-length human GNRHR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor belongs to the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Upon binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately induces the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). Mutations in this gene can cause hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms, with more than 18 transcription initiation sites and multiple polyA signals identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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