Thermo Fisher Scientific NSE2 Polyclonal Antibody
Rabbit polyclonal antibody against Human NSMCE2 (NSE2), suitable for IHC (Paraffin) applications. Antigen affinity-purified, unconjugated, supplied in PBS with glycerol. Recommended dilution 1:200–1:500. For research use only.
- 카탈로그번호
- PA564243
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NSMCE2. Recombinant protein control fragment (Product #RP-104203). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644814 |
Product Specific Information
- Immunogen sequence:
QNNEKFVQFK QQLKELKKQC GLQADREADG TEGVDEDIIV TQS - Highest antigen sequence identity to orthologs:
- Mouse: 79%
- Rat: 77%
Target Information
This gene encodes the large subunit of DNA damage-binding protein, which forms a heterodimer with a small subunit. It plays a role in nucleotide-excision repair. Defective activity of this protein is associated with xeroderma pigmentosum complementation group E (XPE). Mutation analysis is required to confirm whether the defect lies in this gene or in the gene encoding the small subunit. Additionally, Best vitelliform macular dystrophy maps to the same region on chromosome 11q, although no sequence alterations of this gene are found in Best disease patients.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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