Thermo Fisher Scientific WBSCR16 Polyclonal Antibody
Human WBSCR16 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20–1:50 희석 비율로 검증됨. Antigen affinity chromatography로 정제되었으며, 0.05 mg/mL 농도의 액상 형태. 미토콘드리아 융합 및 단백질 번역 연구에 적합.
- 카탈로그번호
- PA563885
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific WBSCR16 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human WBSCR16 (amino acids 119–213) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649537 |
Product Specific Information
Immunogen sequence:
TLLSSKTADV TKVWGMGLNK DSQLGFHRSR KDKTRGYEYV LEPSPVSLPL DRPQETRVLQ VSCGRAHSLV LTDREGVFSM GNNSYGQCGR KVVEN
- Highest antigen sequence identity to orthologs:
- Mouse: 95%
- Rat: 94%
Target Information
WBSCR16 is a guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. It activates OPA1 by exchanging bound GDP for free GTP, driving OPA1 and MFN1-dependent mitochondrial fusion.
This protein plays an essential role in mitochondrial ribosome biogenesis and functions as part of a protein-RNA module consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2, and 16S mitochondrial ribosomal RNA (16S mt-rRNA), which controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of oxidative phosphorylation system subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.