Thermo Fisher Scientific EPHA5 Monoclonal Antibody (5C3)
EPHA5 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot과 ELISA에 최적화. 인간 시료 반응성. PBS 기반 액상 형태로 제공되며 보존제 없음. -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5C3 |
| Immunogen | EPHA5 (NP_004430, 234–333 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PSVVRHLAVF PDTITGADSS QLLEVSGSCV NHSVTDEPPK MHCSAEGEWL VPIGKCMCKA GYEEKNGTCQ VCRPGFFKAS PHIQSCGKCP PHSYTHEEAS
Target Information
EPHA5 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors are implicated in developmental events, particularly in the nervous system. Protein kinases transfer phosphate groups from ATP to substrate proteins, mediating signal transduction and regulating metabolism, transcription, cell cycle, cytoskeletal rearrangement, movement, apoptosis, and differentiation. The tyrosine kinase group regulates cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced, including 58 receptor TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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