Thermo Fisher Scientific ALDH18A1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ALDH18A1 (P5CS). Suitable for Western blot and immunoprecipitation applications. Supplied as unconjugated liquid form at 1 mg/mL. For research use only; not for diagnostic or resale purposes.
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Thermo Fisher Scientific ALDH18A1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 5–10 µL/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human P5CS/ALDH18A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866852 |
Target Information
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta¹-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine, and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia, and hypoprolinemia, and may be associated with neurodegeneration, cataracts, and connective tissue diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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