Thermo Fisher Scientific SEPT2 Polyclonal Antibody, MaxPab
SEPT2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 면역세포화학(ICC/IF)에 사용 가능. Human 반응성, Mouse IgG 아이소타입, 비결합형 액상 제품. PBS(pH 7.4) 버퍼에 보존되며 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SEPT2 (NP_001008491, 1–361 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK STLINSLFLT DLYPERVIPG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV DTPGYGDAIN CRDCFKTIIS YIDEQFERYL HDESGLNRRH IIDNRVHCCF YFISPFGHGL KPLDVAFMKA IHNKVNIVPV IAKADTLTLK ERERLKKRIL DEIEEHNIKI YHLPDAESDE DEDFKEQTRL LKASIPFSVV GSNQLIEAKG KKVRGRLYPW GVVEVENPEH NDFLKLRTML ITHMQDLQEV TQDLHYENFR SERLKRGGRK VENEDMNKDQ ILLEKEAELR RMQEMIARMQ AQMQMQMQGG DGDGGALGHH V
Target Information
Septin 2 is a filament-forming cytoskeletal GTPase required for normal actin cytoskeleton organization. It supports polarized epithelial cell formation by maintaining polyglutamylated microtubules, facilitating vesicle transport, and regulating MAP4 binding to tubulin. Septin 2 is essential for mitotic progression, forming a scaffold at the spindle midplane to maintain CENPE localization and ensure chromosome congression. It also contributes to anaphase chromosome segregation, spindle elongation, ciliogenesis, and collective cell movement.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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