Thermo Fisher Scientific Kir2.2 (KCNJ12) Polyclonal Antibody
Kir2.2(KCNJ12) 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC에 적합합니다. 인간 시료에 반응하며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, -20°C에서 보관합니다.
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 1:600 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human KCNJ12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688601 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%.
Target Information
Inward rectifying potassium channel activated by phosphatidylinositol 4,5-bisphosphate, likely involved in controlling the resting membrane potential in electrically excitable cells. Plays a role in establishing action potential waveform and excitability in neuronal and muscle tissues.
These channels preferentially allow potassium influx rather than efflux. Their voltage dependence is regulated by extracellular potassium concentration, shifting channel opening to more positive voltages as external potassium increases. Inward rectification is mainly due to blockage of outward current by internal magnesium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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