Thermo Fisher Scientific DTNB Polyclonal Antibody
Thermo Fisher Scientific의 DTNB Polyclonal Antibody는 인간 DTNB 단백질을 표적으로 하는 토끼 IgG 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 높은 특이성과 재현성을 제공합니다. 항원 친화 크로마토그래피로 정제되어 연구용으로 최적화되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DTNB. Recombinant protein control fragment (Product #RP-103398). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640811 |
Product Specific Information
Immunogen sequence:
MIAAYDSEGR GKLTVFSVKA MLATMCGGKM LDKLRYVFSQ MSDSNGLMIF SKFDQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 93%
Target Information
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins, and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma, and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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