
Thermo Fisher Scientific SH3PXD2B Polyclonal Antibody
SH3PXD2B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. 인간 시료에 반응하며 ICC/IF에 적합합니다. 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5144870
- 판매단위
- pk
카탈로그
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 431–532). Recombinant protein control fragment: Product # RP-110002 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping Conditions | Wet ice |
| RRID | AB_3091846 |
Product Specific Information
Immunogen sequence:
ASRPNFLAPL PHEVTQLRLG EAAALENNTG SEATGPSRPL PDAPHGVMDS GLPWSKDWKG SKDVLRKASS DMSASAGYEE ISDPDMEEKP SLPPRKESII KS
Antigen sequence identity:
- Mouse: 82%
- Rat: 83%
Target Information
Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides.
Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and localization.
Plays a role in mitotic clonal expansion during the early stage of adipocyte differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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