Thermo Fisher Scientific MRCK gamma Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CDC42BPG(Accession Q6DT37), corresponding to amino acid residues L1393-F1443. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MRCK gamma,uniProtId:Q6DT37-1,ncbiNodeId:9606,antigenRange:1393-1443,antigenLength:1551,antigenImageFileName:PA5-100763_MRCK_gamma_Q6DT37-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100763_MRCK_gamma_Q6DT37-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2850266

Product Specific Information

Antibody detects endogenous levels of total MRCKG.

Target Information

CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.