Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI8F8), TrueMAB
LIPG 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI8F8). Western blot, IHC, ICC, Flow cytometry, IP 등 다양한 응용에 적합. Lyophilized 형태로 제공되며, PBS buffer에 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8F8 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally to modulate lipoprotein metabolism. Overexpression of LIPG reduces HDL cholesterol levels, whereas deficiency increases HDL levels in animals.
LIPG exhibits phospholipase activity and plays roles in lipoprotein metabolism and vascular biology. It belongs to the TG lipase family, characterized by a lid region conferring substrate specificity. LIPG acts as a carboxyl esterase, hydrolyzing high-density lipoproteins, emulsifying triglycerides, and aiding in dietary fat digestion while binding to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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