Thermo Fisher Scientific RAB11FIP1 Polyclonal Antibody
Human RAB11FIP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 세포 내 막 수송 및 엔도솜 재활용 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAB11FIP1 (Product #RP-93848) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646208 |
Product Specific Information
Immunogen sequence:
AKESKKPESR RSSLLSLMTG KKDVAKGSEG ENPLTVPGRE KEGMLMGVKP GEDASGPAED LVRRSEKDTA AVVSRQGSSL NLFEDV
Highest antigen sequence identity to the following orthologs:
- Mouse: 55%
- Rat: 60%
Target Information
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein.
Rab11-FIP1 interacts with Rab GTPases and plays a role in endosomal recycling and membrane trafficking along the phagocytic pathway.
Localized to the recycling endosome, cytoplasmic membrane, and phagosome membranes.
Expressed as five isoforms produced by alternative splicing, with isoform two being the most abundant in brain, lung, testis, small intestine, spleen, and heart.
Isoform two forms a homooligomer and interacts with Rab 4A, Rab 11A, Rab 11B, and Rab 25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-55276_RAB11FIP1_Q6WKZ4-4_Rabbit.svg, PA5-55276_RAB11FIP1_Q6WKZ4-4_Rabbit_PDP.jpeg)
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