Thermo Fisher Scientific DRD2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Dopamine Receptor D2 (DRD2). Validated for IHC and IHC-P applications. High specificity with antigen affinity purification. Supplied as liquid, 1 mg/mL in PBS with sodium azide. For research use only.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 10 µg/mL
- Publications: View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human Dopamine Receptor D2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2094987 |
Product Specific Information
PA1-23584 detects Dopamine Receptor D2 in Human samples.
Target Information
The DRD2 Dopamine Receptor is involved in neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders.
Mutations in DRD2 in mice lead to suppression of reward behavior with morphine and reduction of spontaneous movements, a phenotype resembling Parkinson’s disease.
Three alternatively spliced isoforms have been identified.
DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord.
ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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