Thermo Fisher Scientific PKD2 Polyclonal Antibody
Human PKD2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관. 세포 내 칼슘 항상성 연구 및 신장 질환 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PKD2 (amino acids 786–927). Recombinant protein control fragment: Product #RP-91419 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856217 |
Product Specific Information
Immunogen sequence:
REDLDLDHSS LPRPMSSRSF PRSLDDSEED DDEDSGHSSR RRGSISSGVS YEEFQVLVRR VDRMEHSIGS IVSKIDAVIV KLEIMERAKL KRREVLGRLL DGVAEDERLG RDSEIHREQM ERLVREELER WESDDAASQI SH
Target Information
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains and cytoplasmic N- and C-termini. It may function as an integral membrane protein involved in cell-cell or matrix interactions. The encoded protein is implicated in renal tubular development, morphology, and function, and may modulate intracellular calcium homeostasis and signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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