Thermo Fisher Scientific CD27 Monoclonal Antibody (LG.3A10), FITC
CD27 단백질을 표적하는 FITC 결합 단클론 항체로, Flow Cytometry 및 IHC(F) 실험에 적합합니다. Mouse 시료에 반응하며 Protein G 정제, PBS/BSA 버퍼에 보관됩니다. 짧은 기간 4°C, 장기 보관 시 -20°C에서 보관하십시오.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Assay-dependent
Flow Cytometry (Flow)
- 0.5 µg/1x10^6 cells
- 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Armenian hamster / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LG.3A10 |
| Immunogen | MCD27 tag expressing clones AR0524 and AR0530 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term store at -20°C, avoiding freeze/thaw cycles; store in the dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539288 |
Additional Formats
- Unconjugated: MA5-17902
- Biotin: MA5-17903
- PE: MA5-17905
- Custom conjugation available
Product Specific Information
MA5-17904 targets CD27/TNFRSF7 in FACS, IHC, and IHC (F) applications and shows reactivity with Mouse samples.
The immunogen is mCD27 tag expressing clones AR0524 and AR0530.
Target Information
CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily, including CD40 and CD30. It regulates cell proliferation and death and is primarily expressed on lymphocytes.
High CD27 expression depends on antigen receptor ligation, while CD70 expression requires co-stimulatory or pro-inflammatory signals.
CD27 exists as a disulfide-linked homodimer on thymocytes, peripheral blood T cells, and some B cells. Activation of T cells via TCR-CD3 upregulates CD27 and releases soluble CD27 (sCD27), a prognostic marker for B cell malignancies.
CD27 dysfunction is associated with Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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