Thermo Fisher Scientific MAP2K3 Monoclonal Antibody (OTI5F9), TrueMAB
MAP2K3 단백질 인식용 단일클론 항체로 WB, IHC, ICC/IF 등 다양한 응용 가능. 인간, 마우스, 랫, 개에 반응하며 고순도 액상 형태로 제공. TrueMAB 기술 적용으로 높은 특이성과 재현성 보장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F9 |
| Immunogen | Full length human recombinant protein of human MAP2K3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K3 (MEK3) is a dual-specificity protein kinase involved in cellular signal transduction pathways. It phosphorylates and activates MAPK14/p38-MAPK, and can be activated by insulin. MAP2K3 is necessary for glucose transporter expression, and its activation through RAS oncogene expression leads to constitutive MAPK14 activation and oncogenic transformation of primary cells. Inhibition of MAP2K3 is associated with the pathogenesis of Yersinia pseudotuberculosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported for MEK3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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