Thermo Fisher Scientific Tenascin C (Stromal Marker for Epithelial Malignancy) Monoclonal Antibody (SPM319)
Tenascin C 단백질을 표적하는 인간 유래 단세포항체로, 상피 악성종양의 간질 표지자로 사용됩니다. IHC, ICC/IF, Flow Cytometry에 적용 가능하며, 단백질 A/G로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 2–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM319 |
| Immunogen | Human breast carcinoma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Does not react with Rat.
Target Information
Tenascin is a high molecular weight, multifunctional extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names including cytotactin, hexabrachion protein, J1, myotendinous antigen (MI), and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. Expression of tenascin is associated with both normal and pathological development and growth, while its distribution in normal adult tissue is restricted.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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