Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI2D2), TrueMAB
BFSP1 단백질을 인식하는 Mouse 단일클론 항체로 Western blot 및 IHC(Paraffin)에 적합. 인간 시료 반응성, TrueMAB 형식, 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer에 보관하며 연구용으로만 사용.
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Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI2D2), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–665 of human BFSP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin (product of the BFSP1 gene), are expressed only after fiber cell differentiation begins. Both proteins form a unique cytoskeletal structure called the beaded filament (BF).
Mutations in BFSP1 cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms exist for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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