Thermo Fisher Scientific MYO3A Monoclonal Antibody (8H2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

8H2

Immunogen

MYO3A (NP_059129, 1400 a.a. approximately 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYO3A,uniProtId:Q8NEV4-1,ncbiNodeId:9606,antigenRange:1400-1490,antigenLength:1616,antigenImageFileName:H00053904-M08A_MYO3A_Q8NEV4-1_House_mouse.svg,antigenImageFileNamePDP:H00053904-M08A_MYO3A_Q8NEV4-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: HEEINNIKKK DNKDSKATSE REACGLAIFS KQISKLSEEY FILQKKLNEM ILSQQLKSLY LGVSHHKPIN RRVSSQQCLS GVCKGEEPKI L

Target Information

MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.