Thermo Fisher Scientific CD16/CD32 Monoclonal Antibody (KT1632)
Mouse CD16/CD32 단백질을 인식하는 Rat IgG2a 단클론 항체로, Flow Cytometry 및 Neutralization에 사용됩니다. 비결합형(Unconjugated) 형태이며, 1 mg/mL 농도로 제공됩니다. 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | 0.1 µg/1x10⁶ cells | View 3 publications |
| Neutralization (Neu) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT1632 |
| Immunogen | Mouse CD32/16 Fc gamma III/II |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539396 |
Additional Formats
Product Specific Information
MA5-18012 targets CD32/CD16 in FACS applications and shows reactivity with Mouse samples.
The MA5-18012 immunogen is mouse CD32/16 Fc gamma III/II.
Target Information
CD16 is a 50–65 kDa cell surface molecule that exists in two forms:
- A transmembranous form expressed by natural killer (NK) cells and some T cells
- A phosphatidylinositol-linked form expressed by granulocytes
CD16 is a low-affinity receptor for IgG (FcR III) and mediates antibody-dependent cell-mediated cytotoxicity (ADCC) by NK cells.
CD32 is a 40 kDa glycoprotein acting as a low-affinity receptor for IgG (Fc gamma RII).
It mediates functions such as endocytosis, secretion activation, cytotoxicity, and immunomodulation.
CD32 is expressed by B cells, monocytes, granulocytes, and platelets, and is involved in immune complex phagocytosis and regulation of antibody production by B cells.
Variations in the CD32 gene may increase susceptibility to systemic lupus erythematosus (SLE).
Several transcript variants encoding different isoforms of CD32 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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