Thermo Fisher Scientific PHF7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PHF7. Recombinant protein control fragment (Product #RP-96248). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHF7,uniProtId:Q9BWX1-1,ncbiNodeId:9606,antigenRange:2-101,antigenLength:381,antigenImageFileName:PA5-57594_PHF7_Q9BWX1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57594_PHF7_Q9BWX1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645499

Product Specific Information

Immunogen sequence: KTVKEKKECQ RLRKSAKTRR VTQRKPSSGP VCWLCLREPG DPEKLGEFLQ KDNISVHYFC LILSSKLPQR GQSNRGFHGF LPEDIKKEAA RASRKICFVC

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 80%.

Target Information

Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.