
Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI2F1), TrueMAB
MAPK13 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB 및 ICC/IF에 사용 가능. 인간 유래 재조합 단백질을 면역원으로 제작. 동결건조 형태이며, PBS 버퍼에 trehalose 함유. 연구용으로 스트레스 반응 및 세포 분화 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F1 |
| Immunogen | Full length human recombinant MAPK13 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces extracellular signals related to cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by phosphorylation via MAP kinase kinases or autophosphorylation triggered by MAP3K7IP1/TAB1 interaction.
Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, implicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response.
Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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