Thermo Fisher Scientific FOXJ1/HFH-4 Polyclonal Antibody
FOXJ1/HFH-4 폴리클로날 항체로 인간, 마우스, 랫트 반응성. WB, IHC, ICC, Flow, ELISA 등 다양한 응용 가능. 단백질 A 정제 및 액상 형태로 제공. FOXJ1 관련 자가면역 및 섬모 형성 연구에 적합.
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Thermo Fisher Scientific FOXJ1/HFH-4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human FOXJ1 (amino acids 161–260) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and spontaneous autoimmunity through repression of NF-κB activity. It also inhibits the humoral immune response in B cells. FOXJ1 deficiency leads to spontaneous germinal center formation and is implicated in pathogenic autoantibody development. Additionally, FOXJ1 is essential for cilia formation and left-right axis determination, increasing calpastatin expression for basal body anchoring. Its expression may serve as an early marker of epithelial cell differentiation and recovery.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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