Thermo Fisher Scientific Phospho-ATR (Ser428) Polyclonal Antibody
Phospho-ATR (Ser428) 특이적 Rabbit Polyclonal Antibody로 DNA 손상 반응 연구에 적합. IHC(P) 및 peptide-ELISA에 사용 가능. 고농도(1 mg/mL) 액상 형태로 제공되며 -20°C에서 보관. 연구용 전용 제품.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 정보 없음
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Peptide-ELISA (pep-ELISA)
- Tested Dilution: 1:40,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human ATR around the phosphorylation site of Ser428 (G-I-SP-P-K) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556324 |
Target Information
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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