Thermo Fisher Scientific SLC34A1 Polyclonal Antibody
Human SLC34A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약이며, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC34A1. Recombinant protein control fragment (Product #RP-98434) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2647456 |
Product Specific Information
Immunogen sequence:
PLPVPGGHVM RGTAFAYVPS PQVLHRIPGT SAYAFPSLGP VALAEHTCPC GEVLERHEPL PAKLALEEEQ KPESRLVPKL RQA
Highest antigen sequence identity to orthologs:
- Mouse: 72%
- Rat: 73%
Target Information
Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na⁺/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na⁺/Pi cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells. NPT2 gene expression is crucial for PTH effects on renal phosphate handling. However, renal expression of the sodium/phosphate cotransporter gene NPT2 is not required for regulation of renal 1α-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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